Gene frequency and linkage disequilibrium within the HLA-DRB region in Egyptians using PCR-based reversed hybridization oligonucleotide genotyping
Journal of the Egyptian National Cancer Institute. 1997; 9 (1): 69-74
en Inglés
| IMEMR
| ID: emr-106401
ABSTRACT
HLA class II alleles were studied in 278 Egyptians. Gene frequency as well as linkage [haplotypic association] between HLA-DRB1, HLA- DRB3, HLA-DRB4 and HLA-DRB5 types were defined. A new unexpected haplotype linked with DRB5 was also detected. It was concluded that PCR based reversed hybridization genotyping is a reliable technique for DNA- based HLA-DR typing. In addition, this specific population study has important implications for unrelated bone marrow and other organ donor registries in Egypt
Buscar en Google
Índice:
IMEMR (Mediterraneo Oriental)
Asunto principal:
Antígenos HLA-DR
/
Desequilibrio de Ligamiento
/
Reacción en Cadena de la Polimerasa
/
Hibridación Genética
/
Hibridación de Ácido Nucleico
Límite:
Humanos
Idioma:
Inglés
Revista:
J. Egypt. Natl. Cancer Inst.
Año:
1997
Similares
MEDLINE
...
LILACS
LIS