Some biochemical alterations as influenced by hyperviataminosis D3
Journal of Drug Research of Egypt. 1987; 17 (1-2): 53-62
en Inglés
| IMEMR
| ID: emr-107349
ABSTRACT
The effect of daily administration of vitamin D3 indifferent doses [500, 1000, 5.000, 10.000, 20.000, 50.000 and 100.000 I.U/Kg b.wt.] on serum calcium [Ca], calcium bound protein [Ca BP], inorganic phosphorus [IP], lipoproteins and protein fractions was studied for 4 weeks in albino rats. The data revealed a marked elevation in serum Ca, Ca Bp and IP and a significant increase in beta-lipoprotein. Hypoalbuminemia and subsequent decrease in A/G ratio was observed. A marked increase in y-globulin was found with low doses of vitamin D3. A reversed pattern occurred when high doses of vitamin D3 were given. These results confirmed the harmful effect of hypervitaminosis D3
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Índice:
IMEMR (Mediterraneo Oriental)
Asunto principal:
Ratas
Idioma:
Inglés
Revista:
J. Drug Res. Egypt
Año:
1987
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