Kinetics of the reactions of methyl-2,3-dibromo-3- [4-substituted phenyl] propanoates with piperidine IV
Egyptian Journal of Chemistry. 1992; 35 (2): 149-62
en Inglés
| IMEMR
| ID: emr-107552
ABSTRACT
The rates of elimination of a series of erythromethyl- 2,3-dibromo-3-[4-substituted phenyl] propanoates [1 alpha-d] have been determined conductimetrically in methanol using piperidine as a base. The elimination reactions gave exclusively Z-methyl-2-bromo-3- [4-substituted phenyl] propanoates [2 alpha-d]. The specific rate constants of the reactions gave a good Hammett correlation with p values of 0.39-1.31 which suggest a carbonionic transition state. The results suggested that the reaction proceeds by initial isomerization of the erythro-dibromo-compound to the threo-isomer, which spontaneously eliminates HBr to give [2 alpha-d]
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Índice:
IMEMR (Mediterraneo Oriental)
Asunto principal:
Piperidinas
/
Cetonas
Idioma:
Inglés
Revista:
Egypt. J. Chem.
Año:
1992
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