Quality control applications on diagnostics employed in asparate aminotransferase[AST] and alanine aminotransferase [ALT] determinations

ABSTRACT

In this investigation three lyophilized control sera in the normal and pathological ranges, in addition to patient's samples were used for performance of quality control regulations on two ready-made diagnostics for the determinations of AST and ALT by optimized UV method. Optimal conditions variance [OCV], routine conditions of variance [RCV], in addition to application of quality control and statistical calculation of patient's samples using the CUSUM technique, were applied. The results obtained and proved that UV optimized technique seemed to be reliable precise and accurate. AST and ALT of patient's samples determined by colorimetric and UV optimized technique revealed weak statistical correlation