Does anticardiolipin antibodies predict therapeutic response of nephrotic syndrome patients?

ABSTRACT

Anticardiolipin antibodies [aCL] were measured in 29 patients with nephrotic syndrome [NS] showing different underlying kidney pathology. 8 healthy volunteer persons were taken as a control group. A significantly higher levels of both IgG and IgM aCL were detected in NS patients compared to control. However, no relation was found between aCL levels and age, renal histological pattern or renal function. Unlike serum creatinine level which appear to have predictive value for response to therapy, no association was detected between aCL level and therapeutic response of NS patients