Biochemical markers, a recent trend in the evaluation of the effects of some environmental xenobiotics in experimental animals

ABSTRACT

This experimental work was conducted to determine whether such biomarkers are actually involved in the process of liver fibrosis and cell damage, hence it can be considered as an important tool to predict early latent liver cell damage. It was found that transforming growth factor beta 1 [TGF-B1] was significantly increased in sera of the exposed and recovery groups compared with the control non-exposed group. It was concluded that TGF-beta 1 was a good biomarker for early liver cell damage together with both AST and ALT enzymes