Neuromuscular blockade profile of pipec - uronium in patients with liver cirrhosis
Mansoura Medical Journal. 1999; 29 (3-4): 137-46
en Inglés
| IMEMR
| ID: emr-108367
ABSTRACT
This study aimed to evaluate the neuromuscular blockade profile of pipecuronium in 20 patients suffering from hepatic cirrhosis and divided equally into two groups [a control healthy group and hepatic group submitted to operations to relieve portal hypertension]. All patients were subjected to general anesthesia induced by thiopentone sodium 5 mg/kg, followed by pipecuronium 0.06 mg/kg to facilitate endotracheal intubation and maintained by N2O O2 [2 1] and halothane 0.5-1.0% with 0.01 mg/kg of pipecuronium as maintenance relaxation doses. Endotracheal intubation was successfully performed when TI ratio reached 10% and TOF ratio approximately reached 0% as traced by Datex relaxograph. The onset of action of pipecuronium, duration of clinical relaxation of bolus dose and total dose requirements were measured
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Índice:
IMEMR (Mediterraneo Oriental)
Asunto principal:
Farmacocinética
/
Pipecuronio
/
Fármacos Neuromusculares no Despolarizantes
/
Hemodinámica
Límite:
Femenino
/
Humanos
/
Masculino
Idioma:
Inglés
Revista:
Mansoura Med. J.
Año:
1999
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