Juliflorine susceptibility of animal and human isolates of campylobacter

ABSTRACT

Juliflorine, the main alkaloid isolated from Prosopis juliflora was tested for its antibacterial activity against both the Gram positive and Gram negative bacteria. Filter paper disks impregnated with juliflorine were placed on streaked agar medium. Zones of growth inhibition for Campy lobacter spp occurred at 10 jig per disk. Other enteropathogens [including the species of Salmonella, Shigella, Vibrio, Escherichia, Proteus, Pseudomonas, Klebsiella and Yersinia] were resistant to at least 30 micro g per disk, with the exception of a strain of Aeromonas hydrophilia, Urhich showed some inhibition at 30 micro g per disk. Most of the 25 Campylobacter strains, which were isolated from human clinical and animal sources, showed zones of inhibition greater than 10 mm with 10 micro g of juliflorine