Synthesis, reactions and anticancer activity of some new heterobicylic nitrogen systems bearing acenaphtho [1,2-e] [1,2,4] triazine moiety, part I

ABSTRACT

Some new heterobicylic nitrogen systems, e.g. acetonitrile derivatives bearing acenaphtho [1,2-e] [1,2,4] triazine moiety have been synthesized and reacted with hydrazine hydrate, acetohydrazide, acids, alkalis, thiosemicarbazide and carbon disulphide. Structural assignment of the synthesized products 2-19 were confirmed by elemental analyses and spectral data [[1]H-NMR and [13]C-NMR determinations]. Some selected compounds showed remarkable anticancer activity