Effect of green tea, curcumin and ginger extracts on serum lipid profile in rats after carbon tetrachloride exposure

ABSTRACT

Oxidative stress is a major factor in the pathogenesis of diabetic complications. The current study aimed to investigate the effects of green tea, curcumin and ginger extracts or its combinations on the kidney and liver function for rats exposure to CCL4 injection. The results indicated that, green tea reduced food intake and body weight in rats. The food intake did not show any important variation between both dosage of tested herbs and aqueous extract of green tea, ginger and curcumin. Body weight gain percentage of the control positive group and other groups treated with herbs decreased significantly at [p< 0.05] as compared to the control negative group. The results observed that, rats suffering from CCL4 and treated with of green tea, curcumin and ginger or its combination were associated with decreased serum concentrations of total cholesterol and triglyceride, an increase in the proportion of high-density-lipoprotein cholesterol, and a decreased proportion of low and very-low-density-lipoprotein cholesterols, as compared to positive control group