Acute pancreatitis; management, morbidity and mortality experience in a surgical unit

ABSTRACT

Acute pancreatitis represents a spectrum of disease ranging from a mild, self-limited course to a rapidly progressive, severe illness. The mortality rate of severe acute pancreatitis exceeds 20%, and some patients diagnosed as mild to moderate acute pancreatitis at the onset of the disease may progress to a severe, life-threatening illness within 2-3 days1. A study was conducted in RGH [Now BBH]. January, 1997 to January, 2001. All patients with abdominal pain and having a serum amylase level of five times the normal range, were included in the study. 72 patients were admitted. 29 [40.2%] were males and 42 [59.7%] were females. Male to female ratio was 23. The age of the patients ranged from 7 years to 85 years [average age 40 years]. Disease severity was assessed according to Ranson's criteria. They were managed in a general surgical ward or intensive care unit when indicated. Development of complications and their management done were recorded. Patients stayed in the hospital from 1-21 days with an average period of 8.59 days. 32 [44.44%] recovered uneventfully without any complication while 40 [55.55%] patients developed either local or systemic complications. Overall 10 [13.88%] patients died early in the course of disease i.e. within one week. All of them were above 55 years of age, 6 of them were females and 4 of them were males, mortality ratio for female to male was 32. [1] To study the morbidity and mortality in patients of acute pancreatitis. [2] To evaluate the management of acute pancreatitis in a general surgical unit. Management of mild acute pancreatitis is simple, it needs only supportive treatment. However, the management of severe acute pancreatitis is complex. Mortality is high and the treatment requires individualized approach regarding timing of surgery and choice of technique