Prenatal diagnosis of B-thalassaemia by chorionic villus sampling

Chorionic villus sampling was performed in 124 cases for prenatal diagnosis of beta-thalassaemia over a period of two and a half years. All samples were taken during the late first and early second trimester of pregnancy by transabdominal route using either biopsy forceps or by suction with the help of double needle technique. Twenty six foetuses were found homozygous for beta-thalassaemia