Xanthines drinking during pregnancy as a risk factor for iddm

ABSTRACT

This study was done to evaluate the relation between amount of xanthines intake by pregnant mothers and incidence of IDDM in their children. The study was performed on 201 mothers. They were divided into 2 groups. Group I included 99 mothers in whom one or more of their children are Insulin dependent diabetics. Group II included 102 mothers with normal children. Xanthines intake of mothers of diabetic children was significantly higher than that of mothers of normal children [1334.2 +/- 1119.77 mg/wk vs 875.4 +/- 805.7 mg/wk]. Tea was the highest source of xanthines in both groups [70% vs 64% respectively]. Xanthines derived from coffee was 4.5% in g p I vs 1% in g p II, while that derived from cola was 26%, in gp I and 35% in g p II. We noticed that, high consumption of xanthines and to some extent the way it is served to mothers is associated with increased incidence of insulin dependent diabetes mellitus in their children