effect of comparison of complex carbohydrates and high fibre preparations on post-prandial blood glucose and insulin levels in non-insulin dependent diabetics

ABSTRACT

Since the last decade, the physiological effects of dietary fibres and their possible role in prevention and management of many diseases have been emphasized. The aim of the present work has been to study the possible effects of supplementary different complex carbohydrates, consumed by the Egyptian population, with high fibre preparation, on the post-prandial blood glucose and insulin levels- in non-insulin dependent diabetics. This work has been carried out on 30 NIDD, who have been subjected to oral carbohydrate tolerance tests using boiled rice, boiled potatoes or bread [equivalent to 75 g glucose] at different occasions. Then the same patients have been subjected to the same tests after supplementing each carbohydrate load with high fibre preparation in the form of ceral bran and citrus fruit fibres. Blood glucose and insulin levels have been estimated using RIA technique for the latter. The maximum increment rise of glucose occurred at 90 minutes post-prandial and rice elecited the lowest glucose response, while potatoes elecited the highest one. Similarly rice elecited the lowest plasma insulin response. Supplementation of fibres led to marked and significant reduction of blood glucose level at 60 and 90 minutes in cases of rice and bread [P < 0.05] while the reduction is not significant in cases of potatoes [P > 0.05]. On the other hand addition of high fibre preparation did not affect siguificantly insulin resnonse