Effect of addition of arginine and lysine to casein diets on serum lipids metabolism in rats

ABSTRACT

The effect of feeding casein diets supplemented by amino acids on serum lipids was studied on rats. Three groups of rats were fed casein diets supplemented by lysine or arginine, while the third was fed unsupplemented diet for 8 weeks. The results indicated that rats fed lysine added diets exhibited decrease in body weight comparable with casein only, whereas those fed the arginine showed significant increase for body weight. A significant decrease for serum total lipids, total cholesterol, triglycerides as well as phospholipids were also shown for the group fed the arginine diet, HDL-cholesterol showed no change in supplemented casein by lysine; however, largely increased triglycerides, while total lipids, total cholesterol were fairly increased