Pathology of brucellosis: a review of 88 biopsies

ABSTRACT

A series of 88 biopsy specimens representing a large variety of tissues from 78 proved cases of brucellosis were reviewed. The most frequent histologic pattern was that of nonspecific chronic inflammation characterized by lymphocytic infiltration with variable numbers of histiocytes and plasma cells. Granulomatous inflammation and acute necrotizing and supportive inflammation were encountered less frequently. In none of the biopsies could any morphologic features specific for Brucella infection be identified