Morphologic and immunopathologic spectrum of malignant lymphoma: review of 211 cases

A series of 211 malignant lymphomas in adults were reviewed and classified according to the international working formulation. Of those classified, five [2.4%] were low-grade, 115 [54.5%] intermediate-grade, and 85 [40.3%] high-grade lymphomas. Immunohistologic typing of 106 lymphomas was performed using a panel of monoclonal antibodies against T-and B-cell surface antigens. This revealed 51 [48.1%] B-cell and 41 [38.7%] T-cell lymphomas with 14 [13.2%] indeterminate. These results were compared with those from several recently published studies from other countries. The proportion of aggressive lymphomas in our series appeared to be relatively high. Furthermore, immunohistologic data in our study indicated a significantly higher proportion of T-cell lymphomas as compared to other studies