Renal cell carcinoma: Clinico-pathological retrospective study on Yemeni patients

ABSTRACT

The aim of this study is to highlight the pattern of renal cell carcinoma among Yemeni patients and to correlate this type of cancer with some epidemiological risk factors. The clinical records of 22 patients with renal cell carcinoma, admitted to Al-Gamhoria Teaching Hospital in Aden and Ibn-Khaldoon General Hospital in Lahj Governorate between 1999 - 2002, were studied retrospectively. The mean age of the male patients was 55 years, and the females was 45 years. Renal cell carcinoma was more common in males than females, with a ratio of 21. Smoking habits was found in association with the disease in 73.3% of the male patients. Patients with blood group A were with higher rate [54.6%] of RCC than patients with other blood groups. Renal cell carcinoma affected the left kidney more than the right kidney. One third of the patients presented classical triad [hematuria, pain, mass]. Anemia and increased ESR were found in 77% and 91% of the cases respectively. Renal failure was present in 9% of the cases. Clear cell type was the most common pathological variant of RCC with 77%. We concluded that further studies of RCC in larger series are needed to elucidate the frequency, types, risk factors, and the relationship between blood group and renal cell cancers