Spectrum of thyroid gland disorders in Karachi-DDRRL experience

ABSTRACT

To find out the spectrum of thyroid gland disorders in association with age and gender and to identify histological types of thyroid lesions. Descriptive study. This study was carried out at the Department of Histopathology, DOW University [OJHA campus] Karachi from 1[st] Jan 2010 to 31[st] Dec 2011. The specimens were received in 10% buffered formalin and processed as per routine laboratory procedure and then embedded in paraffin for block preparation. The sections were stained with the routine haematoxylin and eosin method and were studied and diagnosed by a consultant histopathologist. Difficult cases were discussed in Departmental Consultation Committee. Total 208 cases were studied, there was a female predominance 184 [88.5%] and among them majorities were in 3[rd] decade of life. Males were 24 [11.5%] commonly seen in 4[th] decade of life. The ages ranged from 15-75 years, mean age is 30 years. Nodular hyperplasia was the commonest thyroid lesion found. The information in the present study may be considered as a baseline data of thyroid diseases in Karachi and a more elaborate prospective study carried out on a large scale in this country will contribute more to make the things clearer