Study of INF-gamma and IL-6 in patients with Helicobacter pylori
New Egyptian Journal of Medicine [The]. 2010; 42 (6): 554-557
en Inglés
| IMEMR
| ID: emr-125182
ABSTRACT
Helicobacter pylori evade host immune defenses and causes chronic gastritis. Immunity against intestinal pathogens is largely mediated by dendritic cells, yet the role of dendritic cells in acute H pylori infection is largely unknown. The current study was to determine the serum/plasma levels of inflammatory cytokines IL-6 and TNF-alpha in H pylori patients and explain the correlation with disease state, helicabacter pylori Ab IgG and 1gM and urea Breath test. We examined the levels of serum cytokines IL-6 and INF-gamma in 50 patients. Mean serum/plasma levels of IL-6 and INF-gamma in H. pylori patients were significantly higher than those in the healthy controls [P<0.05]. There was a statistically significant correlation between IL-6 levels and INF-alpha in group of positive and negative, IgM. levels of IL-6 and INF-gamma can be used as important parameters for clinical diagnosis and follow up of Helicobacter pylori cases. CRP and ESR is a useful marker ongoing infection but there is Correlation with disease state
Buscar en Google
Índice:
IMEMR (Mediterraneo Oriental)
Asunto principal:
Enfermedad Crónica
/
Estudios de Seguimiento
/
Helicobacter pylori
/
Interleucina-6
/
Interferón gamma
/
Gastritis
Límite:
Femenino
/
Humanos
/
Masculino
Idioma:
Inglés
Revista:
New Egypt. J. Med.
Año:
2010
Similares
MEDLINE
...
LILACS
LIS