[Prevalence of orofacial complication among thalassemic patients in thalassemia center of Qazvin]

ABSTRACT

Thalassemia is the most common monogenic disorder of which Homozygote type [major-beta-thalassemia] is the most severe hemolytic anemia in Iran. Regarding the importance of orofacial complications in these patients and not having enough information about this disease in Iran, it's necessary to do a research in this point as well as knowing and reducing of orofacial complications of thalassemia. This descriptive [Case Series] study was done among all patients of Qazvin thalassemia center [110 patients]. Orofacial examinations [shape of face and nose, maxillary protrusion, oral paleness, delayed eruption of teeth, caries rate and type of occlusion] were done and their relation with medical treatment was evaluated. Statistical analysis was conducted by using SPSS software and Chi[2] test. The prevalence of orofacial complications are ranged as fallow Saddle nose[71.08%], maxillary protrusion [55.5%], paleness of oral mucosa[48.2%], rodent face [30%], deep bite [28.2%], spaces between maxillary anterior teeth [22.7%], open bite [13.6%], delayed eruption of primary [10%] and permanent [8.2%] teeth. Prevalence of occlusion types were decreased as fallow class I,II and III. Caries index [DMFT and dmft] was significantly more among the thalassemic patients than healthy peoples [P<0.05]. The prevalence of orofacial complications of thalassemia was very considerable. This study also showed the importance of early diagnosis and intensive medical treatment in reducing these complications