Extracellular forms of Mycobacterium bovis BCG in the mucosal lymphatic tissues following oral vaccination
International Journal of Mycobacteriology. 2013; 2 (1): 44-50
en Inglés
| IMEMR
| ID: emr-126195
ABSTRACT
Oral vaccination with BCG provides protective systemic immunity against pathogenic mycobacterial challenge. In this study, the anatomical distribution of Mycobacterium bovis BCG following oral vaccination was investigated. Replicating bacteria in the Peyer's patches and mesenteric lymph nodes were present as solitary rods or clusters of two to three bacteria, the majority of which were isolated ex vivo as extracellular forms. Only a minority were shown to be associated with typical antigen-presenting cells. Acid-fast staining of mast cell granules in lymphoid tissues revealed a potential pitfall for these analyses and may explain previous reports of acid-fast 'coccoid' forms of mycobacteria in tissues
Buscar en Google
Índice:
IMEMR (Mediterraneo Oriental)
Asunto principal:
Tuberculosis
/
Vacunas contra la Tuberculosis
/
Inmunidad Celular
/
Tejido Linfoide
/
Ratones Endogámicos BALB C
/
Mycobacterium bovis
Límite:
Animales
Idioma:
Inglés
Revista:
Int. J. Mycobacteriology
Año:
2013
Similares
MEDLINE
...
LILACS
LIS