[Serum lipid levels in psoriasis]

ABSTRACT

Psoriasis is a chronic inflammatory skin disorder. Several studies have indicated that psoriatic patients have higher risk for coronary heart disease and few studies focused on lipid profiles which are important in the pathogenesis of coronary heart disease. This study was designed to investigate the relationship between psoriasis and hyperlipidemia. In this case control study lipid parameters [cholesterol, Triglycerid, High density lipoprotein, Low density lipoprotein, Very low density lipoprotein] of 40 patients with moderate and severe psoriasis [study group] were compared with 40 healthy persons [control group]. Study group matched the control group considering age, sex, BMI, hypertension, habit of smoking and alcohol and body activities. In both groups 19 male and 21 female with a mean age of 37 +/- 16 were studied. Mean lipid level in case group including TG, chol, HDL, LDL, VLDL, was respectively 105/4 +/- 48/5, 180/52 +/- 39/10, 41/22 +/- 1/87, 117/85 +/- 35/52, 21/57 +/- 10/59 and in control group was 103/8 +/- 47/95,173/92 +/- 33/41, 39/25 +/- 9/78 114 +/- 36/07, 20/62 +/- 9/57, which showed no significant difference between the two groups [p>0.05]. According to these results it seems that we don't need to investigate lipid profiles in psoriatic patients