[Comparison of incidence of succinylcholine-induced fasciculation and postoperative Myalgias]

ABSTRACT

Fasciculation and myalgia are common complications of succinylcholine and decrease of incidence and intensity of them will reduce succinylcholine-induced side effects. This study was done to evaluate the severity and prevalence of fasciculation and myalgia after succinylcholine and perform a comparison between three groups. In this case - control study in 2006, 75 patients with ASA I and orthopedic surgery were evaluated in Imam Reza hospital. The patients divided randomly in to three same groups. In first group thiopental and succinylcholine 1.5 mg/kg was injected, in second group propofol 2 mg/kg and succinlycholine 1.5 mg/kg and in third group thiopental and succinylcholine 3 mg/ kg was administered. Fasciculation, intubation quality after 1 min, and myalgia after 24 h were analyzed. Demografic parameters, pain scales and fasciculation data were gathered in a questionnaire and analyzed by SPSS, descriptive statistics and frequency distribution tables. Fasciculation rate was%76 in first group, 80% in second group, and%84 in third groups. Myalgia was%24 in first group,%28 in second group, and%20 in third group. There were no significant differences between group 1 and 2 and also 1 and 3 with respect to fasciculation, Intubation, and post-operative myalgia. We concluded that propofol aggregates muscular relaxation versus thiopental, and low-dose versus high-dose of succinylcholine and chang to phase II block had no differences regarding to these complications