Successful treatment of steroid-refractory autoimmune thrombocytopenia associated with Castleman disease with anti-CD-20 antibody [rituximab]
Hematology, Oncology and Stem Cell Therapy. 2011; 4 (2): 100-102
en Inglés
| IMEMR
| ID: emr-129766
ABSTRACT
Multicentric Castleman disease [MCD] is a lymphoproliferative disorder of incompletely understood etiology and with various clinical presentations. The best therapeutic option for this disease is not well established. MCD is known to be associated with autoimmune phenomena. A 70-year-old female patient of MCD with progressive nodal disease associated with autoimmune thrombocytopenia failed steroid treatment and showed a transient response to intravenous immunoglobulin. The patient achieved complete recovery of her platelet count and a very good response in nodal disease after 3 weekly doses of anti-CD-20 antibody [rituximab]. Anti-CD20 antibody treatment could be a good therapeutic option for MCD, mainly when associated with immune-related disorders
Buscar en Google
Índice:
IMEMR (Mediterraneo Oriental)
Asunto principal:
Enfermedad de Castleman
/
Resultado del Tratamiento
/
Anticuerpos Monoclonales de Origen Murino
Tipo de estudio:
Informe de Casos
Límite:
Anciano
/
Femenino
/
Humanos
Idioma:
Inglés
Revista:
Hematol. Oncol. Stem Cell Ther.
Año:
2011
Similares
MEDLINE
...
LILACS
LIS