Olfactory sensory-cell-number changes with age in albino mice

ABSTRACT

The area of the olfactory neuroepithelium, neuronal cell density, and the estimated total number of cells were studied in 1, 3, 4, 5 and 13 month-old Albino mice. The area increased from 363.7 mm2 for one month old to a maximum of 559 mm2 for 4 month old mice and then declined to 396.2 mm2 by the age of 13 month. Cell density increased with age and reached its maximum of 5.53 x 10 4 per mm2. at 5 moth-old. There was a 64% increase in total number of neurons from 1-4 months of age followed by a 28% decrease between 4 to 13 months of age