[Prevalence of adenovirus infection and the dominant serotype among patients with acute gastroenteritis in Tehran between May 2008 and May 2009]

ABSTRACT

Adenoviruses are double-stranded DNA and non-enveloped viruses. It causes different diseases in human through respiratory, urinary and gastrointestinal tracts. Interestingly, more than fifty serologic types of human adenovirus were distinguished and just serotypes 40 and 41 cause gastroenteritis in human. The purpose of this study was to evaluate the prevalence of adenovirus infection in patients with acute gastroenteritis in the population of Tehran. Between May 2008 and May 2009, 293 stool samples were collected from patients with acute gastroenteritis. After DNA extraction, PCR procedures were performed, using designed primers. Positive adenoviruses samples were analyzed by the software and their serotypes were determined. 6 positive samples of 293 patients recruited to the hospital were children less than 5 years old. Additionally, they were diagnosed as serotype 41 of adenoviruses F group. According to our results, serotype 41 of adenovirus was an important cause of gastroenteritis in less than 5 years old children in population of Tehran