Frequency of malignancy in goiter in Pakistan: a review of 359 thyroidectomics

ABSTRACT

To determine the frequency of malignancy in patients presenting with goiter undergoing for surgery. An observational study. Surgical Department of Social Security Hospital Islamabad January 2002 to February 2011. All patients more than 10 years of age underwent thyroidectomy were included in the study. Postoperatively histopathologies of specimens were evaluated in all patients. A total of 359 patients were operated and post operative histopathology specimens were reviewed. Eleven patients [3.06%] were having carcinoma. among all the thyroid carcinomas, papillary carcinoma was the commonest i.e. [45.45%, 5/11] followed by follicular carcinoma [27.27%, 3/11]. Anaplastic carcinoma was seen in [18.18%, 2/11] and medullary carcinoma seen only in [9.09%, 1/11]. Thyroid carcinoma is not an uncommon condition. Frequency of papillary carcinoma is very high in females among all the thyroid carcinoma