effect of decrease number of neutrophils on their function as effector cells

ABSTRACT

Thirty two [32] male volunteers were chosen for this experiment from persons working at Atomic Energy Authority and checked systematically for their blood picture at the Medical Lab. They were arranged into 4 groups according to their total leucocytic count the control group [12 persons], the leucopenic group [12 persons], the treated group [the same leucopenic persons after 4 weeks treatment] and the persistent leucopenic group [8 persons] where 10 weeks treatment failed to return their blood count to the normal level The phagocytic power of neutrophils and their motility were, estimated by the nitroblue tetrazolium test [N.B.T] and the agarose method; Hanks and Zymosan were used for testing random and directional movement, respectively No statistical change was found in the N.B.T. test in the three groups denoting the negligible effect of leucopenia on the phagocytic power of neutrophils. Concerning the motility the first and third group showed no change, white there was significant increase for both random and directional movement in the second group indicating the beneficial effect of tonics In the motility of neutrophils