[Blood pressure and type 2 diabetes mellitus: impact of the insulin therapy]

ABSTRACT

The incidence of arterial hypertension is by 2-3 times with diabetics than with non-diabetics. Ethiopathogenesis of arterial hypertension in type 2 diabetes is multifactorial insulin-resistance, obesity, hyperlipoproteinemia, age, smoking and probably method of treatment [insulin therapy]. The aim of this retrospective study is to evaluate, over 5 years period, the level of blood pressure and the frequency's progression of arterial hypertension in 35 type 2 diabetes patients treated with insulin. Comparison of 35 type 2 diabetes patients treated with insulin to 35 controls treated with oral hypoglycemic agents. No significant differences were found over 5 years period in mean systolic blood pressure, mean diastolic blood pressure and frequency of arterial hypertension. However, frequency of arterial hypertension was correlated with mean dose of insulin. Our study confirms the long-term results found in the literature reading effects of insulin therapy on blood pressure in diabetic patients