Peritoneal macrophages transfusion in the treatment of chronic postoperative wound infections

ABSTRACT

Four patients with chronic post-operative wound infections and wound gapping that failed to respond to antibiotics were treated by allogeneic macrophage transfusions. No harmful effects were observed following macrophage transfusion and the chronic infections were eradicated in the treated patients with complete healing of wounds. Haemoglobin and white cell count were increased after cell transfusion.It could be concluded that allogeneic macrophage transfusion can combat chronic resistant infections and stimulate both wound healing and haemopoiesis