Efficient discrimination by MIRU-VNTRs of Mycobacterium tuberculosis clinical isolates belonging to the predominant SIT11/EAI3-IND ancestral genotypic lineage in Kerala, India
International Journal of Mycobacteriology. 2013; 2 (4): 244-247
en Inglés
| IMEMR
| ID: emr-140927
ABSTRACT
The present study evaluated the ability of MIRU-VNTRs to discriminate Mycobacterium tuberculosis [MTB] clinical isolates belonging to the SIT11/EAI3-IND ancestral genotypic lineage, which is highly prevalent in Kerala, India. Starting from 168 MTB clinical isolates, spoligotyping [discriminatory index of 0.9113] differentiated the strains into 68 distinct patterns, the biggest cluster being SIT11/48 SIT11 [n = 48]. The present study shows that 12-loci MIRUs and 3 ETRs allowed an efficient discrimination of these isolates [discriminatory indexes of 0.7819 and 0.5523, respectively]
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Índice:
IMEMR (Mediterraneo Oriental)
Asunto principal:
Polimorfismo de Longitud del Fragmento de Restricción
/
Repeticiones de Minisatélite
/
Linaje de la Célula
/
Secuencias Repetitivas Esparcidas
/
Genotipo
Límite:
Humanos
Idioma:
Inglés
Revista:
Int. J. Mycobacteriology
Año:
2013
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