Middle East Journal of Digestive Diseases. 2014; 6 (1): 5-12
en Inglés
| IMEMR
| ID: emr-142145
ABSTRACT
Opioids are widely used for the treatment of malignant and non-malignant pains. These medications are accompanied by adverse effects, in particular gastrointestinal symptoms known as opioid bowel dysfunction [OBD]. The most common symptom of OBD is refractory constipation that is usually stable regardless of the use of laxatives. Narcotic bowel syndrome [NBS] is a subset of OBD described as ambiguous chronic pain aggravated by continual or increased opioid use for pain relief. Pathophysiology of these disorders are not definitely disentangled. Some challenging hypothesis have been posed leading to specific management in order to mitigate the adverse effects. This article is a review of the literature on the prevalence, pathophysiology and management of OBD and NBS.
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Índice:
IMEMR (Mediterraneo Oriental)
Asunto principal:
Dolor
/
Estreñimiento
/
Tracto Gastrointestinal
/
Enfermedades Gastrointestinales
/
Analgésicos Opioides
/
Narcóticos
Límite:
Humanos
Idioma:
Inglés
Revista:
Middle East J. Dig. Dis.
Año:
2014
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