Study of plasma lipoproteins in patients with ischaemic heart diseases under beta-adrenoceptor blockade

ABSTRACT

In this study the effect of propranolol on total cholesterol, HDL, LDL, VLDL, and apolipoprotein A and B in 30 patients with IHD with or without hypertension in comparison to 10 control patients with I.H.D not receiving B Blockers. Our results demonstrated that Propranolol caused significant increase in very low density lipoprotein and triglycerides levels. Propranolol caused insignificant decrease in high density lipoprotein. Insignificant increase in apoprotein B/apoprotein A ratio. The above changes in these variants may increase the risk of ischaemic heart disease