Clinical, oro dental and cytogenetic studies in some cases of papillon-lefevre syndromes and prepubertal periodontitis

ABSTRACT

Prepubertal peripdontitis is a rapidly prognessive form of early onset periodontitis leading to destruction of the periodontal support of the primary and secondary dentition. The aim of this study is to determine the basics for genetic mapping of six Egyptian cases suffering from prepubertal periodontitis and its variants. After completion of clinical assessment, cytogenetic study was performed for all cases including chromosomal analysis and plain X-ray for their hands. The gentic study revealed arachnodactyly of their hands, However no radiographic deformity of their fingers was detected. The cytogenetic study for all patients did not show any abnormality. This study might have important implications on oral public health, and in diagnosis and treatment of periodontitis