Does the longer application of anodal-transcranial direct current stimulation increase corticomotor excitability further? a pilot study
Basic and Clinical Neuroscience. 2012; 3 (4): 28-35
en Inglés
| IMEMR
| ID: emr-146019
ABSTRACT
Anodal transcranial direct current stimulation [a-tDCS] of the primary motor cortex [M1] has been shown to be effective in increasing corticomotor excitability. We investigated whether longer applications of a-tDCS coincide with greater increases in corticomotor excitability compared to shorter application of a-tDCS. Ten right-handed healthy participants received one session of a-tDCS [1mA current] with shorter [10 min] and longer [10+10 min] stimulation durations applied to the left m1 of extensor carpi radialis muscle [ECR]. Corticomotor excitability following application of a-tDCS was assessed at rest with transcranial magnetic stimulation [TMS] elicited motor evoked potentials [MEP] and compared with baseline data for each participant. MEP amplitudes were increased following 10 min of a-tDCS by 67% [p=0.001] with a further increase [32%] after the second 10 min of a-tDCS [p =0.005]. MEP amplitudes remained elevated at 15 min post stimulation compared to baseline values by 65% [p=0.02]. The results demonstrate that longer application of a-tDCS within the recommended safety limits, increases corticomotor excitability with after effects of up to 15 minutes post stimulation
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Índice:
IMEMR (Mediterraneo Oriental)
Asunto principal:
Proyectos Piloto
/
Encuestas y Cuestionarios
/
Análisis de Varianza
/
Potenciales Evocados Motores
/
Estimulación Magnética Transcraneal
/
Lateralidad Funcional
Límite:
Femenino
/
Humanos
/
Masculino
Idioma:
Inglés
Revista:
Basic Clin. Neurosci.
Año:
2012
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