Management of acute and perforated/gangrenous appendicitis: cost analysis of two antibiotic regimens

ABSTRACT

Two combinations clindamycin and gentamycin-[Group A]' and 'Metronidazole, ampicillin and cloxacillin -[Group B]' were used as part of the treatment in 71 patients of acute and perforated appendicitis. The infection rate in group A was 10% and in Group B was 14%. The results being comparable, the cost of treatment for Group A per patient was considerably less. In patients with peritonitis due to perforated appendix, wound sepsis was high despite appropriate antibiotics