Genes and molecular probes in haemoglobinopathies

ABSTRACT

Red cell genetic disorders constitute a major public health problem in many parts of the world. The analysis of human DNA using recombinant technology is fast becoming an integral part of the diagnosis and prevention of several types of major haemoglobinopathies. This review presents advances made in this important field and describes current methods used for antenatal diagnosis of haemoglobinopathies as a prelude to genetic counselling