Obstructive sleep apnea among patients with type 2 diabetes: prevalence and effect on glycemic control

ABSTRACT

Obstructive sleep apnea [OSA] is a highly prevalent comorbidity of type 2 diabetes. The aim of this work is to determine the risk of OSA in patients with type 2 diabetes and its effect on the glycemic control. This study was conducted at Assiut University Hospital Sleep Unit, 52 patients with type 2 diabetes were included, all patients underwent an overnight polysomnography [PSG] and glycosylated hemoglobin [HbAlc] measurement. A total of 62% [n 32] of patients with type 2 diabetes had OSA[apnea-hyponea index [AHI] >/= 5 events/hour]. 27% [n=14] of patients had mild OSA [5 /= 30]. There was a significant positive correlation of HhAlc levels with apnea hypopnea index, a widely accepted marker of the severity of OSA [P<0.001]. Also, we found that increasing OSA severity was correlated with increasing HbAlc levels [p<0.001]. The mean llbAlc values were 8.2% for those without OSA, 9.4% for mild OSA, 10.1% for moderate OSA and 10.6% for severe OSA. We concluded that the prevalence of OSA in this study was 62% and increasing severity of OSA is associated with poorer glycemic control. Therefore, identifying and treating OSA in patients with type 2 diabetes may improve their glycemic control