[Complications leading to hospitalization due to consumption of anti-TB drugs in patients with tuberculosis in Gorgan, Iran [2007-12]]

ABSTRACT

Anti tuberculosis drugs therapy is the most effective method for controling the tuberculosis [TB]. Early detection and appropriate treatment can prevent the TB-drug resistance. This study was carried out to determine the complications leading to hospitalization due to consumption of anti-TB drugs in patients with tuberculosis. In this descriptive-analytic study, 1550 records of patients with TB in urban and rural health centers of Gorgan, north of Iran were assessed during 2007-12. Checklist consists of demographic and clinical data for each patient was recorded in a questionare. 44 cases experienced the complications of anti-TB drugs. 27 [61.4%] of cases with complications were women. 77.3% and 22.7% of patients affected with pulmonary and extra pulmonary tuberculosis,respectively. 38.6% of patients were diabetic. The hepatic complication was seen in 37 cases [84.1%]. Skin and other complications were seen in 5 and 2 cases, respectively. There was not any relationship between drug complications and other disases. Hepatic damage is the most common complication leading to hospitalization in tuberculosis patients using anti-TB drugs