Stereochemistry of the reaction of primary amenies and hydrazine tives with activated alkynes
Alexandria Journal of Pharmaceutical Sciences. 1990; 4 (1): 73-76
en Inglés
| IMEMR
| ID: emr-15226
ABSTRACT
The reaction of methyl 3-[4-substituted phenyl]-propynoates I a, b and 3-[4-chlorophenyl]-1-phenyl-2-propyn-1-one II with 2-pyridylmethylamine III in methanol gave the corresponding E- and Z-enamine derivatives, respectively. The reaction of II with 4-amino-5-mercapto-3-methyl-1, 2, 4-triazole IV yielded a mixture of E, Z-enamine and imine derivatives. PMR and IR spectra confirmed the configuration assigned to the enamine products. Treatment of II with 2-hydrazinobenzothiazole V gave a mixture of the hydrazone and pyrazole derivatives
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Índice:
IMEMR (Mediterraneo Oriental)
Asunto principal:
Química
/
Hidrazinas
Idioma:
Inglés
Revista:
Alex. J. Pharm. Sci.
Año:
1990
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