multicenter point-prevalence survey of antibiotic use in 13 Chinese hospitals

The use of antibiotics is considered a major determinant of the development of resistance in organisms. This study assessed current patterns of antibiotic prescription and provides background for quality improvement in general hospitals in Hubei, China. A point-prevalence study was performed in November 2008. All inpatients on the day of the survey were included in the analysis. On the day of the study, 6904 patients [56%] were receiving antibiotic therapy; the highest rate occurred in the ICU [90%], and the lowest occurred in the medical wards [39%]. The most commonly used antibiotics were beta-lactam antibiotics, including cephalosporins [40%] and piperacillin [19%], followed by fluoroquinolones [14%]. Our data indicated a high rate of antibiotic use in Chinese hospitals. These findings suggest important areas for intervention and the implementation of antibiotic stewardship policies in Chinese hospitals. A multi-faceted strategy should be implemented at the national level in China and should include education, regulation, and greater financial support from the government