Outcome of azithromycin treatment of active trachoma in Omani schoolchildren
EMHJ-Eastern Mediterranean Health Journal. 2003; 9 (5-6): 1026-1033
en Inglés
| IMEMR
| ID: emr-158239
ABSTRACT
A prospective cohort study was made of 386 first-grade primary-school children in Oman with active trachoma and 386 matched controls without trachoma. All children were educated about trachoma prevention. In addition, trachoma cases were treated with a single dose of oral azithromycin [20 mg/kg]. Trachoma status was evaluated after 6 weeks, 6 months and 12 months. The follicles and inflammatory signs of active trachoma resolved 6 weeks or more after azithromycin treatment. The protection against subsequent trachoma infection cycles was optimal at 6 months [85.2% of cases, 99.0% of controls infection-free] but declined at 12 months [66.7% of cases, 98.2% of controls infection-free]. Clinical evaluation seems to be a useful tool to evaluate the response of azithromycin to active trachoma cases in schoolchildren in a country with limited resources
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Índice:
IMEMR (Mediterraneo Oriental)
Asunto principal:
Examen Físico
/
Servicios de Salud Escolar
/
Factores de Tiempo
/
Esquema de Medicación
/
Método Simple Ciego
/
Tracoma
/
Tamizaje Masivo
/
Administración Oral
/
Resultado del Tratamiento
/
Antibacterianos
Tipo de estudio:
Ensayo Clínico Controlado
/
Estudio de tamizaje
Límite:
Femenino
/
Humanos
/
Masculino
Idioma:
Inglés
Revista:
East Mediterr Health J.
Año:
2003
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