Relation between serum ferritin and liver and heart MRI T2* in beta thalassaemia major patients
EMHJ-Eastern Mediterranean Health Journal. 2013; 19 (8): 727-732
en Inglés
| IMEMR
| ID: emr-159000
ABSTRACT
There is a need for higly accurate non-invasive methods for assessing organ iron content in thalassaemia patients. This study evaluated the relation between serum ferritin level, liver enzyme levels and hepatitis C antibody and liver and heart iron deposition assessed by MRI T2 Data were obtained from the medical records of 156 thalassemia major patients in Tehran. There was a moderate negative correlation between serum ferritin and liver MRI T2 relaxation time [r= -0.535] and a weak negative correlation between serum ferritin and heart MRI T2 relaxation time [r= -0.361]. Hepatitis C infection and liver enzyme levels did not confound or modify the relation between ferritin and liver or heart MRI T2. Liver and heart MRI T2* readings were poorly correlated [r= 0. 281]. Routine evaluation of liver and heart iron content using MRI T2 is suggested to better evaluate the haemosiderosis status in thalassemia patients
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Índice:
IMEMR (Mediterraneo Oriental)
Asunto principal:
Imagen por Resonancia Magnética
/
Estudios Transversales
/
Anticuerpos contra la Hepatitis C
/
Ferritinas
/
Corazón
/
Hierro
/
Hígado
/
Pruebas de Función Hepática
Tipo de estudio:
Estudio de prevalencia
Límite:
Femenino
/
Humanos
/
Masculino
Idioma:
Inglés
Revista:
East Mediterr Health J.
Año:
2013
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