Prevalence of coeliac disease among adult patients with autoimmune hypothyroidism in Jordan
EMHJ-Eastern Mediterranean Health Journal. 2014; 20 (1): 51-55
en Inglés
| IMEMR
| ID: emr-159137
ABSTRACT
The prevalence of coeliac disease among patients with autoimmune hypothyroidism has not been studied before in Jordan and other Arab countries. A cross-sectional record-based review was made of all adult autoimmune hypothyroidism patients who attended a referral centre in Jordan, during an 8-month period. Coeliac disease in these patients was diagnosed by the attending physician based on positive serological tests for anti-endomysial antibodies IgA and IgG followed by duodenal biopsy to confirm the diagnosis of coeliac disease. Of 914 patients recruited, 117 [12.8%] were seropositive for coeliac disease. Of 87 seropositive patients who underwent duodenal biopsy, 39 had positive histological findings of coeliac disease [44.8%]. Extrapolating from these findings the overall rate of coeliac disease among autoimmune hypothyroidism patients was estimated to be 5.7%. In multivariate logistic regression coeliac disease was significantly associated with older age [> 40 years], presence of other autoimmune diseases, vitamin B12 deficiency and anaemia
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Índice:
IMEMR (Mediterraneo Oriental)
Asunto principal:
Enfermedades Autoinmunes
/
Tiroiditis Autoinmune
/
Pruebas Serológicas
/
Estudios Seroepidemiológicos
/
Estudios Transversales
/
Técnicas para Inmunoenzimas
Tipo de estudio:
Estudio de prevalencia
Límite:
Femenino
/
Humanos
/
Masculino
Idioma:
Inglés
Revista:
East Mediterr Health J.
Año:
2014
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