Your browser doesn't support javascript.
loading
Characteristics of mixed prolactin and adrenocorticotropin secreting pituitary adenomas and the differences in patients with merely prolactin-secreting adenomas
Saudi Medical Journal. 2014; 35 (3): 248-254
en Inglés | IMEMR | ID: emr-159366
ABSTRACT
To evaluate the characteristics of pituitary adenomas that produce both prolactin and adrenocorticotropin. Between 2002 and 2011, we reviewed the data of 336 patients undergoing transsphenoidal surgery at Shandong Provincial Hospital Affiliated to Shandong University, Jinan, China. Patients were divided into 2 subgroups patients with mixed prolactin and adrenocorticotropin secreting adenomas, and patients with merely prolactin-secreting adenomas. Clinical and endocrinological data, imaging, histopathological reports, and outcomes were reviewed. Differences between the 2 groups were statistically analyzed, and p<0.05 was considered statistically significant. Compared to patients with merely prolactin-secreting adenomas, patients with mixed prolactin and adrenocorticotropin secreting adenomas were younger [p<0.001], had higher incidences of headaches and dizziness [p=0.021], progressive obesity [p<0.001], menstrual disorders [p=0.006], polyuria and polydipsia [p<0.001], hypertension [p=0.001], diabetes mellitus [p=0.001], and had higher rates of postoperative hyponatremia [p<0.001]. Recurrence rates in patients with prolactin-secreting adenomas were 19.1% and patients with mixed prolactin and adrenocorticotropin secreting adenomas were 35.1% [p=0.023]. However, the endocrine normalization rate in mixed prolactin and adrenocorticotropin secreting adenomas was lower [p=0.004]. Careful long-term follow-up is needed for patients with mixed prolactin and adrenocorticotropin secreting adenomas
Buscar en Google
Índice: IMEMR (Mediterraneo Oriental) Idioma: Inglés Revista: Saudi Med. J. Año: 2014

Similares

MEDLINE

...
LILACS

LIS

Buscar en Google
Índice: IMEMR (Mediterraneo Oriental) Idioma: Inglés Revista: Saudi Med. J. Año: 2014