Prophylactic antibiotics in patients with chronic suppurative otitis media undergoing tympanoplasty: a comparative study of augmentin versus amoxicillin

ABSTRACT

To compare the usefulness of prophylactic augmentin compared with amoxicillin in patients undergoing tympanoplasty. This study was conducted in 3 hospitals namely Aseer Central Hospital, Saudi German Hospital and Al-Namas Hospital in Aseer Region. This study included 32 CSOM patients without any complications. They were randomized into 2 groups, Group A [n=16], who received intravenous 1.2 mg augmentin after the induction of the anesthesia followed by 7 days oral augmentin in a doses of Ig Bid or Group B [n=16] who received amoxicillin 500 mg thrice a day for one week. The clinical success was significantly higher among patients who received augmentin [Group A] compared with those who received amoxicillin [Group B] in preventing the postoperative infection [p=0.033]. Among patients in Group A, 15 cases [93.7%] had successful take of graft compared with 10 cases [62.5%] in group B. The use of prophylactic augmentin antibiotic is more effective in preventing early post-tympanoplasty infection compared with amoxicillin