CTX-M ESBL enzyme in Escherichia coli from urology patients in Rawalpindi, Pakistan
JPMA-Journal of Pakistan Medical Association. 2006; 56 (12): 576-578
en Inglés
| IMEMR
| ID: emr-164791
ABSTRACT
To detect CTX-M phenotype utilizing disc diffusion and MIC testing in Escherichia coli isolated from a tertiary care urology setting. Fifty single, non duplicate ESBL producing isolates from a tertiary care urology hospital were evaluated for the presence of CTX-M phenotype. Initially all the urinary isolates were tested for ESBL production. The isolates were identified by using API 20E galleries and screened for ESBL production by combination disc. Representative 4 ESBL isolates were sent to Antibiotic Resistance Monitoring and Reference Laboratory [ARMRL], Health Protection Agency, Colindale, London, UK where those were further subjected to MIC testing by agar dilution and E-test strips. A total of 4 ESBL producing E. coli isolates were characterized to be CTX-M on phenotypic characterization. The overall yield of CTX-M phenotypes was 75%.The emergence of CTX-M from Pakistan is alarming; however, further studies are required to study the epidemiology and genetic characterization of CTX-M types of ESBLs
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Índice:
IMEMR (Mediterraneo Oriental)
Idioma:
Inglés
Revista:
J. Pak. Med. Assoc.
Año:
2006
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