Pregnancy in Turner syndrome variants, report of 9 cases andreview literature

ABSTRACT

Turner syndrome is one of the most common cytogenetic disorders in human with an incidence of one case in about 2500 female live born children. Most patients have sexual infantilism and pregnancy is rare. Bahner reported the first case of a pregnant Turner patient and then the pregnancy of such patients has not been considered impossible. Nine patients out of 243 Turner patients referred to Kariminejad-Najmabadi Pathology and Genetic Centre [Tehran, Iran] during 1979 to 1997 have experienced spontaneous pregnancy. These 24 pregnancies lead to 14 cases of spontaneous abortion [64%], 3 cases of intra-uterine fetal death [14%] and 5 cases of live birth [20%], consisted of one case of congenital heart disease and one case of Down syndrome. We have not any information about two other cases. In this article we discuss the chance and outcome of pregnancy in Turner syndrome