Skin diseases in kidney transplant recipients

ABSTRACT

The aim of this study was to evaluate the frequency of skin diseases in kidney transplant recipients. This cross-sectional study was performed on 233 kidney transplant recipients in Ekbatan Hospital of Hamedan in 2004. The patients were examined by a dermatologist and diagnosis was made on the basis of clinical observations. Biopsies and scraping of the lesions were taken whenever necessary. Of the patients, 226 [97%] suffered from one or more skin lesions. The most common lesions were drug related, including hypertrichosis, gingival hyperplasia, acne, and cushingoid feature which were detected in 86.7% of the patients. Also, infectious and premalignant or malignant lesions [actinic keratosis, squamous cell carcinoma, and basal cell carcinoma] were seen in 48.9% and 14.2% of the patients. The mean duration of immunosuppressive therapy was significantly higher in patients with infectious skin diseases [P < .001]. Skin lesions are a significant problem in kidney transplant recipients. A careful monitoring of these patients is recommended in order to detect these lesions in early stages and treat them